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We use human intestinal biopsies to study drug absorption and toxicity inside an in-house engineered microfluidic system. For this we are using Fluigent pumping system to create a controlled flow inside the microfluidic chip while having simple and robust interface for medium throughput applications.
Evita van de Steeg, PhD
Hossein Eslami Amirabadi, PhD
TNO Zeist /
Zeist, The Netherlands / December, 2019
The Experimental Soft Matter Physics group uses solutions provided by Fluigent for controlling fluid flow in their research on microfluidic production of liquid crystal shells, and electrospinning as well as microfluidic wet spinning of liquid crystal core-functionalized polymer fibers. Moreover, the low-pressure units are used in a microfluidic device for measuring interfacial tension that was developed in the group.
Université du Luxembourg / Luxembourg / December, 2019
With my team, we have been using Fluigent systems for about 10 years for a great variety of projects, ranging from single cell trapping and manipulation to the application of multi-modal mechanical stimulation in organ-on-a-chip platforms. Fluigent systems are in general extremely accurate, they are user-friendly and their very fast response time is ideal for some of our applications requiring quick switching between different pressures.
Séverine Le Gac
University of Twente /
Enschede, The Netherlands / July, 2019
I have been using MFCS™-EZ pumps throughout my PhD and postdoc since 2007. When we started the lab in 2016, we equipped it with MFCS™-EZ pumps. Their ease of use and precision makes them a reliable ally for our experiments.
Jean-Léon Maitre
Curie Institute / Paris, France / August, 2018
Our laboratory has been using Fluigent equipments in the lab since several years and we have always been satisfied of Fluigent products and services. I personally used the Flow EZ in my PhD and Postdoc research work and it allowed me to perform experiments that were not possible with other microfluidic flow control technologies. Indeed, Fluigent offered us the possibility to precisely and dynamically control the flow rate in the lower pressure and flow rate range, thanks to the very low pressure resolution of the 25 mbar Flow EZ. This ability was key in the development of our platform to create cell aggregates in flow conditions with dielectrophoresis.
Dr. Jonathan Cottet
The Microfluidics Laboratory of the ESPCI has used the Fluigent equipments for almost 10 years. Pressure-driven fluid handling brought a lot of flexibility and robustness in our daily experiments. The MFCS™-EZ is a strong and reliable device, able to adapt to all types of microfluidic experiment. The range complete by adding flow sensors able to transform the MFCS™-EZ into a full flow-rate piloting system with the FRP. Our laboratory trust Fluigent products, engineers, software developers as well as the entire team that makes every day a great job.
Fabrice Monti
MMN Laboratory, IPGG / Paris, France / February 4, 2015
“As a team working in Droplet based microfluidic we’ve been using Syringe pumps. Involved in a new research program, we decided to switch our former equipment for a Fluigent flow rate control solution Microfluidic flow control system (MFCS™-EZ) + (FLOWELL, old Flow-Rate Platform, with Flow Rate Control Module). We observed a real improvement as this system based on the control of pressure is more responsive and stable. In our specific application microfluidic systems usually need some time to stabilize while the Fluigent solution allows a quick start or stop. It is also very flexible as it allows stopping and restarting the droplet manipulation, the change of reservoir or sample during an experiment, with almost no impact on the experiment. Besides, the pressure regulation enables to limit the maximum pressure applied to the chip and allow us to preserve the integrity of our chip especially those with long channels.”
Raphael Calbrix
Plate-forme de Chimie Biologique Intégrative de Strasbourg (PCBIS) / Ecole supérieure de biotechnologie Strasbourg (ESBS) FRANCE
“We have found the Fluigent equipment to be very helpful to our microfluidic research on various fluid mechanics and transport problems. For example, in order to investigate diffusion of nano particles inside a microfluidic channel, we originally tried to generate a concentration gradient along a closed channel by constantly flowing solutes across one open end. We recognized the need to generate a steady flow that minimized pressure fluctuation or other perturbations, which we found inevitable with motor-driven pumps. With aid of the Fluigent Microfluidic flow control system (MFCS™-EZ) and Flow-Rate Platform (FRP), we were able to achieve a fluctuation-free, perfectly steady flow, which allowed us to generate a constant concentration along the targeted area. The new research results we have obtained were made possible by the high quality and ease of use of the Fluigent equipment.”
Howard Stone and Sangwoo Shin
Department of Mechanical and Aerospace Engineering / Princeton University, USA
We use Fluigent precision pumps to control flow in a Cancer-on-Chip set up with top and bottom flow. The biological material is thin slices (0.3 mm) derived from tumors (patient derived xenograft or directly from surgical resection in the hospital). The tumor slices are maintained under constant flow for one to two weeks without loss of tissue integrity, viability or proliferation.
Dik van Gent, Associate Professor
Department of Molecular Genetics
Erasmus University Medical Center
Rotterdam, the Netherlands / December 2019
Fluigent systems grant at the same time high-precision real-time control and long-term stability of flow, which are both crucial for my applications. Fluigent team is always available to help designing and optimizing flow control strategies and keen to develop their systems to meet the needs of the state-of-the-art microfluidic applications.
Eleonora Secchi
ETH Zürich, Institute of Environmental Engineering
Zürich, Switzerland / December 2019
“We have bought Fluigent flow control solution (MFCS™ + FLOWELL, old Flow-Rate Platform, with Flow Rate Control Module) to replace our usual high precision syringe pumps to generate monodisperse microfluidic droplets. Fluigent solution provides a very efficient and reliable flow rate control as well as a significantly higher stability at low flow rates in comparison with syringe pump-based systems. The whole set-up including both hardware and software is very intuitive and easy to work with.”
Michael Ryckelynck Associate Professor
Institut de Biologie Moléculaire et Cellulaire (I.B.M.C.) / UPR-9002 du CNRS, FRANCE
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